Tuesday, December 9, 2014

Genetic musings


               This evening, walking back home after an intellectually charged session in Machine control, we witnessed a kid of maybe 12-14 years walking with her mother. Our attention was drawn to this mother-child duo because the facial features of the kid looked very familiar to us. For a moment, it was surreal because we did not expect to see that face so far away from home. It took a few seconds for us to realise that it was indeed someone else and in fact the similarity in features was most probably due to a case of Down's syndrome. It is a genetic disorder where an extra copy of the 21st chromosome is present. Instead of two of it, three are present. This anomaly expresses itself by resulting in delay in growth, a relatively low IQ, language disability, etc.
               
The kid we knew from home was very active. Although we read from literature that Down syndrome causes low IQ, we can say from experience that, that kid was not lacking in it. He was very well-behaved and had a decent memory.

               
We find it very remarkable that, what is essentially a copying error can lead to such a dramatic affliction in humans. In fact this error is quite common, occurring once in every 1000 babies born in a year! To date, we do not know what leads to the presence of three pairs of the 21st chromosome. The result of the extra chromosome is that, since the chromosomes hold the genes, the bodily functions regulated by the 21st get over-expressed. Meaning - the increased production of certain chemicals. So, at the most fundamental and critical level, our existence is not controlled by us. Our consciousness is housed several layers above. To borrow a computer systems analogy, the hardware on which the software of consciousness runs is not autonomous. The software cannot correct for any hardware changes no matter how advanced it may be. We don't like it, but we cannot deny saying that we are 'being kept alive' by a machinery about which we understand very little and have a superficial control. That is our position.  

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